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Despina

♀ Girl

Pronounced des-PEE-nah /dɛsˈpi.nɑ/Medium

Meaning: From Greek despoina, 'a lady; a mistress' — also a title of the goddess Persephone, and a title of the Virgin Mary in Greek tradition; we note the divine titleLow

In 30 seconds: A lady; a mistress: Despina is Greek 'a lady'. Lyrical, classic, and warm (said 'des-PEE-nah').

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Origin LowGreek

MeaningFrom Greek despoina, 'a lady; a mistress' — also a title of the goddess Persephone, and a title of the Virgin Mary in Greek tradition; we note the divine title

U.S. rank (2025)#15508 ↘ Falling

2025 U.S. births5 girls (0.00% of U.S. girls)

Peak year1976

Total births (all-time)≈ 1,522

Popularity in the U.S. · SSA data

U.S. births per year (Social Security Administration, 1880–present). Pink marker = peak year.

SSA data updated May 2026. How we source & verify this data.

History & Origin

Despina comes from Greek despoina, 'a lady; a mistress' — also a title of the goddess Persephone and, in Greek Christian tradition, a title of the Virgin Mary (we note the divine title). A lyrical, classic name (said 'des-PEE-nah'; nickname Pina).

In the U.S. it appears in Greek families. Rare, a-lady at the root, and classic.

Did you know? Despina means 'a lady; a mistress' in Greek — also a title of the goddess Persephone, and a title of the Virgin Mary in Greek tradition — a lyrical, classic name (we note the divine title; said 'des-PEE-nah').

Overall data confidence 45%

References — Despina — divine title noted

Variations

DespoinaDespena

Nicknames

Pina

Famous Bearers

Famous bearers coming soon.

If you like Despina…

Kalliope— a sound-neighbor Greek girls' name

Delfina— echoes that soft -na sound

Deonna— shares Despina's Greek roots

Elaina— a similarly popular pick

Selina— shares Despina's Greek roots

Explore names like Despina

By themeuncertain greek

By meaningGod / Divine

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Frequently Asked

What does the name Despina mean?

Despina is Greek for 'a lady; a mistress' — also a divine title (Persephone, the Virgin Mary). We note the divine title.

How do you pronounce Despina?

It's said des-PEE-nah /dɛsˈpi.nɑ/ — three syllables, stress on the second.

Is Despina a boy or girl name?

Despina is a girl's name.

How popular is Despina?

Despina is a rare name in the U.S.